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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168eb47d7d1601df067ff8801a2dd80c2877c2e218c8982c517233fc7cc64344' 
  AND token = 'wFaHKCzzAc5/O7FpftrFGgtPqtYybfgM1HPOo3QL1Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}