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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '359a482e485555843536804bd1133185e37c74867b2d4c5d5e2c3633f7055b45' 
  AND token = '3tjRVvBdUTysacNdsB3xK12LvIyoNlCEdjsxjMzHM08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}