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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a354a44f14ae6c86c7d6906de3cb2a4437836a40cfd4dc566926b713450e350c' 
  AND token = 'V0Zm/Vl7uD5S13yS+2yYUfeAHM/y3WemEn0LEc3x8zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}