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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b52896145c98c981817f8750583f8e9c7bda0289515b8fdec22a78c1fe91f4c' 
  AND token = 'toGXGy1F/sRX1b//IPsGYw6bjZZn0DnLB/YJbCmfCiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}