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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af91339de9e0309f1be42803ab09a32fc78ff1389828d36f19def7d21f0d52fa' 
  AND token = '9NPlgBQT/joQWDnIe8TSt+NFR7Q2/GW3sqIV1OL2Ho0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}