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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0550fe13f99ada427f9e2a559bdfcbbff4c56e43f5def7584fda3ed5201f1320' 
  AND token = 'k2n9RkxklasYrpG6py0VZY5dbY+OG3Z8lO3Nm22BLPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}