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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e89a2ce9584910892a744c6cd91b11380545859b463d0f8885e351cda957fce' 
  AND token = 'qFWHxZ3o/6WDaUpoeFR4x9MRS1mlquhhVIO57sRYuPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}