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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9125c7a18d1a217cfb74e0feb9ed81d3f78ea92bf38f0fe4bd3cfe6956d7df74' 
  AND token = '2b0tR9hJnIGWtflJT+BqCJQWfLlHZVeU6mQVchxQ63I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}