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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d79f9903ca25cf92f5e9a558a3b07220eb4ba3a4bfb8d79b64b1ac44877ba1b' 
  AND token = 'pPPICZavYyrYYwrDQ8UpbueSUcretoNTfhHR67UZLus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}