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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29c79b0a75b1cb0f5057dc85110db7d206e43a9e125de19cf10251e20d742a11' 
  AND token = 'mINKT6o/ETUPJixrsL+5ok+BM5iHki1tPVGUzoboqM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}