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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4dc4cd4d0842a2c7b84002fdce19e4940f005bd2a67f0256cfdb4d279ae49f' 
  AND token = 'YshWr4d1kYP3+fNm2yGuCmN0aD2jUyqUUVNU0Ff43ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}