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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25e5ad6c384fcfbdccc242ef820bb4f586b04d1379c2675fc93e39c855bc466' 
  AND token = 'QZUu0Vnom4ze/in999whM00MR4RfAz2L6ZfciB+Rud8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}