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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18396238b4da0b1be9d1569e42864606d0293e7d48e07db1dfd1bde237baf1a1' 
  AND token = 'g/wJLzrc4cWZOf+/t3k30D7BCe62WZmoslfWC0IhnWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}