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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b75253f737f61daf62560c908c0ef13a65f786c771438a3b93a7335f69af86' 
  AND token = 'm78pk4ksY3ekXMequM701C3sPy4YiXbRT8J+PZ/TmCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}