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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52034859d84444bf9c2a5a9560accf0eaa3188360aa0ad1bdbdc87d8250abfd2' 
  AND token = 'zw7ktTS4+ua+wxDXnOxT0HlnVtKLY4nE9I5XB4L5W6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}