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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18fc8f57cdb9bd0ed90fafa15d03e0cade9a4fe4ca20781f44e7e3fca95cf047' 
  AND token = 'ZK2d3+4dJN0fzj3IFVEcQMmJ8oWJlxgzbTAC1qMfOjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}