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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44189555fc93151143ef963fc7c6641f8155c5e84629914566906b956a6e45b5' 
  AND token = 'qVHPDAavip19QL4t++AQOLvTdd94i0Fxhj4ww25Mr1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}