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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f83050a622c137f953ea2fd283583f62678adedb06b59594a3e2e2882af382f' 
  AND token = 'HkjW8zRp/5U16IQbs/geiANEV/iaA4cDU8FSxkFSusQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}