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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9563ed4e22ea0c012c741796465a5dcf238fc86374944e0cb12e4d4f5a92f00b' 
  AND token = '4eCPnjdUNwTRpSDOAbdPUc8GqCEBJR5tiJHOz5wHm+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}