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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38fad379f0c7a753a0d5361a65b7d0a0e9d834ab12172a931788a383a89402a7' 
  AND token = 'G/Z09Z6V5D4jMDAkWTih5e2rYb48tANrOvKz+/eU2zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}