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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25037a0225ffa66a5bbb6127f94cfa47076f6135ba780548dc38e5b12094d3d' 
  AND token = '9Hdd8n7OOxvIPcpkFq0bDSpGdNylE3EXUn7v3Qb5WOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}