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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00dbe0cbfe50708d7bbd253ef22b1531223cd3b5c4eb111ec189e4089f984cab' 
  AND token = 'KMfS0kk2TlLPoCYUxMxDjzj9ib3teD/zk41dAfimjVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}