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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b89fdb8663125ef926beae4d2b607a48caa2ef0020c0ff31ffb116192e6e5c22' 
  AND token = '3Ql6UsEXScea+hj9WUCGxRIKpPqUmIx3HeRKnppWGS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}