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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb91018c7b4a90f954014834bc44606f8872141177983b24b88e0df753d84e51' 
  AND token = 'NjyKFbt0GQna7emesMtgy/4WyhY7UcwXLIhTnbAYKro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}