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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3693201e36642d8110c9171052333bb671f7b688e0ffb0bb541a4b1c3d478a2' 
  AND token = 'VusCuUB+tJnx8UqB0uUtheOZIxilI1rv5H+Zh52Wi+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}