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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f1342690fa9652c3452fe41c69b4f1b5e75088bfef4dafa9285a59b63e35c4' 
  AND token = '0F4/4xnKh1n7UQ3ZRb4WQl71tc+XJ83D6fcBizOzwZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}