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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d719ed8a50c1b2f29d7f7b170429f7a3d0cb5301f20ff755227af0b4264f90b' 
  AND token = '34wkKgTJpKVoQnyt6Sa9VYhyVhPOpQNq/KWSdCHkLtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}