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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22ac64712f052fd973e63e095672415f044d991d18d651f0657b659b26480da' 
  AND token = 'AYzkL5EnKbzZS0GVy6IJfN0i7m3qyzLTsPjAnKTQewg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}