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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebfbfc55052c6de3a1276023d9e28e105d2977f43cf4d5e77c2d84db05482a85' 
  AND token = 'DSFWiR50GYbx2D4SxlQ4LkWe0evyqAyw3uhvxEJcLkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}