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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250155a8405911d5c3447fbe8b8e703d3ceb2863a57c39e1c74e435709d1398e' 
  AND token = 'shqgy2miJ3up5//p0cC4ZhCqPgzEhvwQ27C/EeQKnGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}