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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f7e4d0c37e9587f91d95f73d44e441cfcace118da9d2fe02435559c328d27a5' 
  AND token = 'cdU3qGBH+CZWmPMprt5Z2Za6KzXuaoFwg8A8LXKMwME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}