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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c1e6e5d86b782fa855bcd490d0003d8933e1a80d65705ef3195be836628a49' 
  AND token = 'qiZXwLQQarMeHC+N608gIT2zp3Twm8HITUGFC0M79oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}