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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d7e8af6fe7f9799bfe4d4f048c2e850791420d75523a8c7f3acba6eb6088bac' 
  AND token = '+xZw9zCL2zYzaHvg6HyV7o8zCeVwMXi5oGJ1FMlb+es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}