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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4808b3312e7ff7b00fde21a3188af18bfcffb649b843b1db4cfd098bd9f49058' 
  AND token = 'qZw+03HzHg5b2FiHUO0dKkmn9RU48exdduxh7b4mNWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}