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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25b62bcad6a6530801fade6dcb1dbbd8e2b18eb6799bcce885e8a9a29635b7b' 
  AND token = 'qa8UVIyrQ3trS+FGpynDHMsF3C7xOd39X21iBof8Kis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}