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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d06544db609c13825fddd9e0fd4ba3a03dd0306a0a8f0d5ce7e785f6ad09702' 
  AND token = 'DRnWUsXZBeY4Okp+KDdbcioSobyA0zIeE1Nf580E484=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}