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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9c47ff356021ed14734f4eb1b7601bf8d9eb986e3d2dafabc2112d9bcfc50c2' 
  AND token = '5n9tIBiz+vStFlTW5qKOqcGoLVl5u9XcupnOLGt4H5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}