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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef3d621cad2bee272afca2655e61208408e15cb67de435ffdac3d8b0a4d5ffa' 
  AND token = 'iW9FdUU9huk9ohaK4kDVySIHxO9PFV/UERsQbMiqIPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}