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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2871b72a9a764b6b3a07a9c65814e245e159e5a74acf1f34ff46aa13c6aac98' 
  AND token = 'sXwy2pIMx7LnduFo8ZhbxKtzYk6kFnbpxB++tk4sAyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}