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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15546abab8e4920a2fb3c538878bb26cffb64f77974ed78d3b74ccf2eeda0b1' 
  AND token = 'gu0E8RAfX/V8X3qQl9Heu7EKKBcE8a8zJ/cQzNkWmrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}