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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f710513ec4e689cea217c59ff687587fcd2df008eda10a10ebc43287e7a8ec' 
  AND token = 'nr8Iv4U0vyQ9iSJiBJIBwOzQUQiUgTe51DWXOF/GvfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}