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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e53f4ce4290323f20e178db1c53eb73fe4d341a979c579b4a9ad6a453487de' 
  AND token = 'pOyijZWwukXpvXHkHiIvOAcnhXHZW4efYo9NBkuAPSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}