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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df926dcafca01b97ebd25eb28677e82519037efa2026d360ad1a76e9f64de387' 
  AND token = 'BZM4LQ7LnO8wJCj1KdYxtj8bZFIycgC8xFLDr8iG5Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}