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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd041db19c12d88f45539ac1cb724c6e4356134bb2a42d2e693832d5caee1546' 
  AND token = 'yjEWECKFvY+sa6/AuFSW+uk9naAvo6lLgO/EfOYEXvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}