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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28178d759ecbf96ba398b29f581ee14ecfbc58470b2ed027d5dfd7fef2efd86' 
  AND token = 'CybGP4W3RGHM7yLzw0eTiPVQiSAfrpf4q3QagBJ61T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}