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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127f829ffbdf2002af9628cd4c32f4c2a6c3de57f2c02a4a269961bb29b8f2a1' 
  AND token = 'w7DLTOsqgkyaTbE4VT3KRbM1KE1GZ6DniWCtqgdzWCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}