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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf072ee443128d6e89273ffe45537e9ae2468cdc1613448197a52696d0bb31c2' 
  AND token = 'djxBtMkpfUzjvA1pDApDFCJP/wpKawUbCJ20z6BW6pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}