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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a371b3c7cf5d7e983eade33076c22f8950c1724565c056f7a97b03e29fdc89' 
  AND token = '4lWgTU9+PvoSpS/M/ayM/71LQswbFTSZx4fatBC18jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}