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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946aa9f21f3216339e60ad7ed0d889e70eb68e6f5a8a98af99de0f00cb6aa42d' 
  AND token = 'Ro28lSuSftG4z2oduwk3ZXsB48dlxlxcXE1boBLeqwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}