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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f531af1904768012b01c4a1e56d5cf4a4838ed37181eae0079d29f1fde9ca01' 
  AND token = '5KgpMLItye6d7u4qSeWfVpmthZXLNJSBHGuKXx06S6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}